People

Jill Hollenbach, PhD, MPH

Professor In Residence
Neurology

The Hollenbach Lab specializes in analysis of the extremely polymorphic human leukocyte antigen (HLA) and killer immunoglobulin-like receptor (KIR) immunogenetic systems. In addition to their critical role in transplantation, over 100 infectious, autoimmune and pharmacological disease phenotypes and cancers are associated with genetic variation of HLA and KIR, which also have functional interaction with one another.

Holly Ingraham, PhD

Professor
Cellular Molecular Pharmacology

The Ingraham Lab investigates mammalian sex-differences and how hormone signaling in the brain and in the gut-brain axis affects sex-dependent physiological endpoints in females, especially during aging.

Roshanak Irannejad, PhD

Asst Professor in Residence
Cardiovascular Research Inst

Isha Jain, PhD

Assistant Investigator
Biochemistry and Biophysics

Natalia Jura, PhD

ASSOC PROF IN RES-HCOMP
Cardiovascular Research Inst

Sarah Knox, PhD

Professor
Cell and Tissue Biology

Deanna Kroetz, PhD

Department Chair & Professor
Bioengineering

The overarching goal of the Kroetz laboratory is to understand the molecular basis of interindividual variability in drug response and toxicity. Genomic association studies are used to identify genes and pathways involved in common toxicities associated with cancer therapy, including taxane-induced peripheral neuropathy and bevacizumab-induced hypertension. Functional genomic studies are then used to define the role of these genes and pathways in the dose-limiting toxicities. A second area of research is on the role of ABC transporters in drug resistance and physiologic function.

Diana Laird, PhD

Full Prof In Residence
Ob/Gyn, Reproductive Sciences

Our work focuses on three interrelated questions: do all developing germ cells have equal potential to give rise to functional eggs or sperm; how do environmental inputs affect germ cells during development, and what is the role of germ cells in ovarian and systemic aging? Using mouse models, human cells, and naked mole rats, we explore these questions in the real-world contexts of prenatal exposures to endocrine-disrupting chemicals and psychosocial stress as well as genetic causes of infertility such as Fragile X Primary Ovarian Insufficiency.

Anna Victoria Molofsky, MD, PhD

Associate Professor In Res
Psychiatry

Shaeri Mukherjee, PhD

Associate Professor
Microbiology and Immunology

Geeta Narlikar, PhD

Professor
Biochemistry and Biophysics

Melanie Ott, MD, PhD

Director
Medicine

My laboratory is interested in the molecular mechanisms of viral pathogenesis. We focus on a variety of viruses including HIV-1, Hepatitis B and C Virus (HBV and HCV), Zika and SARS-CoV-2. We believe that identifying common host pathways involved in different viruses can lead to the discovery of panviral therapeutics. All are important public health problems and with HCV and HIV sharing common traits including high propensities to establish chronic infections and a lack of efficient vaccines, and Zika and SARS-CoV-2 causing global pandemics leading to death and disability.

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