Shaeri Mukherjee, PhD

Professor
Microbiology and Immunology
+1 415 476-2826
Publications: 

Cross-family small GTPase ubiquitination by the intracellular pathogen Legionella pneumophila.

Molecular biology of the cell

Steinbach A, Bhadkamkar V, Jimenez-Morales D, Stevenson E, Jang GM, Krogan NJ, Swaney DL, Mukherjee S

A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response.

Nature cell biology

Subramanian A, Wang L, Moss T, Voorhies M, Sangwan S, Stevenson E, Pulido EH, Kwok S, Chalkley RJ, Li KH, Krogan NJ, Swaney DL, Burlingame AL, Floor SN, Sil A, Walter P, Mukherjee S

Cross-family small GTPase ubiquitination by the intracellular pathogen Legionella pneumophila.

bioRxiv : the preprint server for biology

Steinbach AM, Bhadkamkar VL, Jimenez-Morales D, Stevenson E, Jang GM, Krogan NJ, Swaney DL, Mukherjee S

A conserved megaprotein-based molecular bridge critical for lipid trafficking and cold resilience.

Nature communications

Wang C, Wang B, Pandey T, Long Y, Zhang J, Oh F, Sima J, Guo R, Liu Y, Zhang C, Mukherjee S, Bassik M, Lin W, Deng H, Vale G, McDonald JG, Shen K, Ma DK

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

Nature

Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, White KM, O'Meara MJ, Rezelj VV, Guo JZ, Swaney DL, Tummino TA, Huettenhain R, Kaake RM, Richards AL, Tutuncuoglu B, Foussard H, Batra J, Haas K, Modak M, Kim M, Haas P, Polacco BJ, Braberg H, Fabius JM, Eckhardt M, Soucheray M, Bennett MJ, Cakir M, McGregor MJ, Li Q, Meyer B, Roesch F, Vallet T, Mac Kain A, Miorin L, Moreno E, Naing ZZC, Zhou Y, Peng S, Shi Y, Zhang Z, Shen W, Kirby IT, Melnyk JE, Chorba JS, Lou K, Dai SA, Barrio-Hernandez I, Memon D, Hernandez-Armenta C, Lyu J, Mathy CJP, Perica T, Pilla KB, Ganesan SJ, Saltzberg DJ, Rakesh R, Liu X, Rosenthal SB, Calviello L, Venkataramanan S, Liboy-Lugo J, Lin Y, Huang XP, Liu Y, Wankowicz SA, Bohn M, Safari M, Ugur FS, Koh C, Savar NS, Tran QD, Shengjuler D, Fletcher SJ, O'Neal MC, Cai Y, Chang JCJ, Broadhurst DJ, Klippsten S, Sharp PP, Wenzell NA, Kuzuoglu D, Wang HY, Trenker R, Young JM, Cavero DA, Hiatt J, Roth TL, Rathore U, Subramanian A, Noack J, Hubert M, Stroud RM, Frankel AD, Rosenberg OS, Verba KA, Agard DA, Ott M, Emerman M, Jura N, von Zastrow M, Verdin E, Ashworth A, Schwartz O, d'Enfert C, Mukherjee S, Jacobson M, Malik HS, Fujimori DG, Ideker T, Craik CS, Floor SN, Fraser JS, Gross JD, Sali A, Roth BL, Ruggero D, Taunton J, Kortemme T, Beltrao P, Vignuzzi M, García-Sastre A, Shokat KM, Shoichet BK, Krogan NJ

"Make way": Pathogen exploitation of membrane traffic.

Current opinion in cell biology

Noack J, Mukherjee S

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing.

bioRxiv : the preprint server for biology

Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, O'Meara MJ, Guo JZ, Swaney DL, Tummino TA, Hüttenhain R, Kaake RM, Richards AL, Tutuncuoglu B, Foussard H, Batra J, Haas K, Modak M, Kim M, Haas P, Polacco BJ, Braberg H, Fabius JM, Eckhardt M, Soucheray M, Bennett MJ, Cakir M, McGregor MJ, Li Q, Naing ZZC, Zhou Y, Peng S, Kirby IT, Melnyk JE, Chorba JS, Lou K, Dai SA, Shen W, Shi Y, Zhang Z, Barrio-Hernandez I, Memon D, Hernandez-Armenta C, Mathy CJP, Perica T, Pilla KB, Ganesan SJ, Saltzberg DJ, Ramachandran R, Liu X, Rosenthal SB, Calviello L, Venkataramanan S, Lin Y, Wankowicz SA, Bohn M, Trenker R, Young JM, Cavero D, Hiatt J, Roth T, Rathore U, Subramanian A, Noack J, Hubert M, Roesch F, Vallet T, Meyer B, White KM, Miorin L, Agard D, Emerman M, Ruggero D, García-Sastre A, Jura N, von Zastrow M, Taunton J, Schwartz O, Vignuzzi M, d'Enfert C, Mukherjee S, Jacobson M, Malik HS, Fujimori DG, Ideker T, Craik CS, Floor S, Fraser JS, Gross J, Sali A, Kortemme T, Beltrao P, Shokat K, Shoichet BK, Krogan NJ

CHC22 clathrin mediates traffic from early secretory compartments for human GLUT4 pathway biogenesis.

The Journal of cell biology

Camus SM, Camus MD, Figueras-Novoa C, Boncompain G, Sadacca LA, Esk C, Bigot A, Gould GW, Kioumourtzoglou D, Perez F, Bryant NJ, Mukherjee S, Brodsky FM

Systematic Identification of Host Cell Regulators of Legionella pneumophila Pathogenesis Using a Genome-wide CRISPR Screen.

Cell host & microbe

Jeng EE, Bhadkamkar V, Ibe NU, Gause H, Jiang L, Chan J, Jian R, Jimenez-Morales D, Stevenson E, Krogan NJ, Swaney DL, Snyder MP, Mukherjee S, Bassik MC

A Legionella pneumophila Kinase Phosphorylates the Hsp70 Chaperone Family to Inhibit Eukaryotic Protein Synthesis.

Cell host & microbe

Moss SM, Taylor IR, Ruggero D, Gestwicki JE, Shokat KM, Mukherjee S

How to rewire the host cell: A home improvement guide for intracellular bacteria.

The Journal of cell biology

Cornejo E, Schlaermann P, Mukherjee S

Innate immunity kinase TAK1 phosphorylates Rab1 on a hotspot for posttranslational modifications by host and pathogen.

Proceedings of the National Academy of Sciences of the United States of America

Levin RS, Hertz NT, Burlingame AL, Shokat KM, Mukherjee S

Legionella pneumophila subversion of host vesicular transport by SidC effector proteins.

Traffic (Copenhagen, Denmark)

Horenkamp FA, Mukherjee S, Alix E, Schauder CM, Hubber AM, Roy CR, Reinisch KM

Subversion of membrane transport pathways by vacuolar pathogens.

The Journal of cell biology

Alix E, Mukherjee S, Roy CR

Modulation of Rab GTPase function by a protein phosphocholine transferase.

Nature

Mukherjee S, Liu X, Arasaki K, McDonough J, Galán JE, Roy CR

Opposing action of casein kinase 1 and calcineurin in nucleo-cytoplasmic shuttling of mammalian translation initiation factor eIF6.

The Journal of biological chemistry

Biswas A, Mukherjee S, Das S, Shields D, Chow CW, Maitra U

Bacterial FIC Proteins AMP Up Infection.

Science signaling

Roy CR, Mukherjee S

Nuclear import is required for the pro-apoptotic function of the Golgi protein p115.

The Journal of biological chemistry

Mukherjee S, Shields D

Fragmentation of the Golgi apparatus: an early apoptotic event independent of the cytoskeleton.

Traffic (Copenhagen, Denmark)

Mukherjee S, Chiu R, Leung SM, Shields D

Characterization of Drosophila nitric oxide synthase: a biochemical study.

Biochemical and biophysical research communications

Sengupta R, Sahoo R, Mukherjee S, Regulski M, Tully T, Stuehr DJ, Ghosh S

A caspase cleavage fragment of p115 induces fragmentation of the Golgi apparatus and apoptosis.

The Journal of cell biology

Chiu R, Novikov L, Mukherjee S, Shields D