Professor
M_Microbiology and Immunology
+1 415 476-2826
Publications
A conserved Hsp70 phosphorylation regulates cell cycle progression after DNA damage.
bioRxiv : the preprint server for biology
Canonical and phosphoribosyl ubiquitination coordinate to stabilize a proteinaceous structure surrounding the Legionella-containing vacuole.
bioRxiv : the preprint server for biology
Legionella uses host Rab GTPases and BAP31 to create a unique ER niche.
bioRxiv : the preprint server for biology
Cross-family small GTPase ubiquitination by the intracellular pathogen Legionella pneumophila.
Molecular biology of the cell
A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response.
Nature cell biology
Cross-family small GTPase ubiquitination by the intracellular pathogen Legionella pneumophila.
bioRxiv : the preprint server for biology
A conserved megaprotein-based molecular bridge critical for lipid trafficking and cold resilience.
Nature communications
Non-canonical activation of the ER stress sensor ATF6 by Legionella pneumophila effectors.
Life science alliance
"Make way": Pathogen exploitation of membrane traffic.
Current opinion in cell biology
A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing.
bioRxiv : the preprint server for biology
CHC22 clathrin mediates traffic from early secretory compartments for human GLUT4 pathway biogenesis.
The Journal of cell biology
Systematic Identification of Host Cell Regulators of Legionella pneumophila Pathogenesis Using a Genome-wide CRISPR Screen.
Cell host & microbe
A Legionella pneumophila Kinase Phosphorylates the Hsp70 Chaperone Family to Inhibit Eukaryotic Protein Synthesis.
Cell host & microbe
How to rewire the host cell: A home improvement guide for intracellular bacteria.
The Journal of cell biology
Innate immunity kinase TAK1 phosphorylates Rab1 on a hotspot for posttranslational modifications by host and pathogen.
Proceedings of the National Academy of Sciences of the United States of America
Legionella suppresses the host unfolded protein response via multiple mechanisms.
Nature communications
Legionella pneumophila subversion of host vesicular transport by SidC effector proteins.
Traffic (Copenhagen, Denmark)
Structure of the Legionella effector AnkX reveals the mechanism of phosphocholine transfer by the FIC domain.
The EMBO journal
Subversion of membrane transport pathways by vacuolar pathogens.
The Journal of cell biology
The Golgi protein p115 associates with gamma-tubulin and plays a role in Golgi structure and mitosis progression.
The Journal of biological chemistry
Opposing action of casein kinase 1 and calcineurin in nucleo-cytoplasmic shuttling of mammalian translation initiation factor eIF6.
The Journal of biological chemistry
Bacterial FIC Proteins AMP Up Infection.
Science signaling
Nuclear import is required for the pro-apoptotic function of the Golgi protein p115.
The Journal of biological chemistry
Fragmentation of the Golgi apparatus: an early apoptotic event independent of the cytoskeleton.
Traffic (Copenhagen, Denmark)
Characterization of Drosophila nitric oxide synthase: a biochemical study.
Biochemical and biophysical research communications
A caspase cleavage fragment of p115 induces fragmentation of the Golgi apparatus and apoptosis.
The Journal of cell biology