Anna Victoria Molofsky, MD, PhD

Associate Professor In Res
Psychiatry
Publications: 

Publisher Correction: Circuit and molecular architecture of a ventral hippocampal network.

Nature neuroscience

Gergues MM, Han KJ, Choi HS, Brown B, Clausing KJ, Turner VS, Vainchtein ID, Molofsky AV, Kheirbek MA

Regulatory T-cells inhibit microglia-induced pain hypersensitivity in female mice.

eLife

Kuhn J, Vainchtein ID, Braz JM, Hamel K, Bernstein M, Craik V, Dahlgren MW, Ortiz-Carpena J, Molofsky A, Molofsky A, Basbaum A

In situ and transcriptomic identification of microglia in synapse-rich regions of the developing zebrafish brain.

Nature communications

Silva NJ, Dorman LC, Vainchtein ID, Horneck NC, Molofsky AV

Genetically Encoded, pH-Sensitive mTFP1 Biosensor for Probing Lysosomal pH.

ACS sensors

Chin MY, Patwardhan AR, Ang KH, Wang AL, Alquezar C, Welch M, Nguyen PT, Grabe M, Molofsky AV, Arkin MR, Kao AW

Reactive astrocyte nomenclature, definitions, and future directions.

Nature neuroscience

Escartin C, Galea E, Lakatos A, O'Callaghan JP, Petzold GC, Serrano-Pozo A, Steinhäuser C, Volterra A, Carmignoto G, Agarwal A, Allen NJ, Araque A, Barbeito L, Barzilai A, Bergles DE, Bonvento G, Butt AM, Chen WT, Cohen-Salmon M, Cunningham C, Deneen B, De Strooper B, Díaz-Castro B, Farina C, Freeman M, Gallo V, Goldman JE, Goldman SA, Götz M, Gutiérrez A, Haydon PG, Heiland DH, Hol EM, Holt MG, Iino M, Kastanenka KV, Kettenmann H, Khakh BS, Koizumi S, Lee CJ, Liddelow SA, MacVicar BA, Magistretti P, Messing A, Mishra A, Molofsky AV, Murai KK, Norris CM, Okada S, Oliet SHR, Oliveira JF, Panatier A, Parpura V, Pekna M, Pekny M, Pellerin L, Perea G, Pérez-Nievas BG, Pfrieger FW, Poskanzer KE, Quintana FJ, Ransohoff RM, Riquelme-Perez M, Robel S, Rose CR, Rothstein JD, Rouach N, Rowitch DH, Semyanov A, Sirko S, Sontheimer H, Swanson RA, Vitorica J, Wanner IB, Wood LB, Wu J, Zheng B, Zimmer ER, Zorec R, Sofroniew MV, Verkhratsky A

Circuit and molecular architecture of a ventral hippocampal network.

Nature neuroscience

Gergues MM, Han KJ, Choi HS, Brown B, Clausing KJ, Turner VS, Vainchtein ID, Molofsky AV, Kheirbek MA

Microglial Remodeling of the Extracellular Matrix Promotes Synapse Plasticity.

Cell

Nguyen PT, Dorman LC, Pan S, Vainchtein ID, Han RT, Nakao-Inoue H, Taloma SE, Barron JJ, Molofsky AB, Kheirbek MA, Molofsky AV

Astrocytes and Microglia: In Sickness and in Health.

Trends in neurosciences

Vainchtein ID, Molofsky AV

The immune system and psychiatric disease: a basic science perspective.

Clinical and experimental immunology

Bennett FC, Molofsky AV

Adventitial Stromal Cells Define Group 2 Innate Lymphoid Cell Tissue Niches.

Immunity

Dahlgren MW, Jones SW, Cautivo KM, Dubinin A, Ortiz-Carpena JF, Farhat S, Yu KS, Lee K, Wang C, Molofsky AV, Tward AD, Krummel MF, Peng T, Molofsky AB

Demystifying Microglia: And Now the Work Begins.

Immunity

Dorman LC, Molofsky AV

Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength.

Neuron

Kelley KW, Ben Haim L, Schirmer L, Tyzack GE, Tolman M, Miller JG, Tsai HH, Chang SM, Molofsky AV, Yang Y, Patani R, Lakatos A, Ullian EM, Rowitch DH

Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development.

Science (New York, N.Y.)

Vainchtein ID, Chin G, Cho FS, Kelley KW, Miller JG, Chien EC, Liddelow SA, Nguyen PT, Nakao-Inoue H, Dorman LC, Akil O, Joshita S, Barres BA, Paz JT, Molofsky AB, Molofsky AV

Dynamism of an Astrocyte In Vivo: Perspectives on Identity and Function.

Annual review of physiology

Poskanzer KE, Molofsky AV

Astrocyte-encoded positional cues maintain sensorimotor circuit integrity.

Nature

Molofsky AV, Kelley KW, Tsai HH, Redmond SA, Chang SM, Madireddy L, Chan JR, Baranzini SE, Ullian EM, Rowitch DH

Expression profiling of Aldh1l1-precursors in the developing spinal cord reveals glial lineage-specific genes and direct Sox9-Nfe2l1 interactions.

Glia

Molofsky AV, Glasgow SM, Chaboub LS, Tsai HH, Murnen AT, Kelley KW, Fancy SP, Yuen TJ, Madireddy L, Baranzini S, Deneen B, Rowitch DH, Oldham MC

Chapter 36 Mechanisms of Astrocyte Development.

A.V. Molofsky, C. Hochstim, B. Deneen, D. Rowitch

Regional astrocyte allocation regulates CNS synaptogenesis and repair.

Science (New York, N.Y.)

Tsai HH, Li H, Fuentealba LC, Molofsky AV, Taveira-Marques R, Zhuang H, Tenney A, Murnen AT, Fancy SP, Merkle F, Kessaris N, Alvarez-Buylla A, Richardson WD, Rowitch DH

Regulated temporal-spatial astrocyte precursor cell proliferation involves BRAF signalling in mammalian spinal cord.

Development (Cambridge, England)

Tien AC, Tsai HH, Molofsky AV, McMahon M, Foo LC, Kaul A, Dougherty JD, Heintz N, Gutmann DH, Barres BA, Rowitch DH

Astrocytes and disease: a neurodevelopmental perspective.

Genes & development

Molofsky AV, Krencik R, Krenick R, Ullian EM, Ullian E, Tsai HH, Deneen B, Richardson WD, Barres BA, Rowitch DH

Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing.

Nature

Molofsky AV, Slutsky SG, Joseph NM, He S, Pardal R, Krishnamurthy J, Sharpless NE, Morrison SJ

Diverse mechanisms regulate stem cell self-renewal.

Current opinion in cell biology

Molofsky AV, Pardal R, Morrison SJ

Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation.

Nature

Molofsky AV, Pardal R, Iwashita T, Park IK, Clarke MF, Morrison SJ