Asst Professor in Residence
M_Cardiovascular Research Inst
Publications
Subcellular activation of β-adrenergic receptors using a spatially restricted antagonist.
Proceedings of the National Academy of Sciences of the United States of America
cAMP signaling: a remarkably regional affair.
Trends in biochemical sciences
Selective activation of intracellular β1AR using a spatially restricted antagonist.
bioRxiv : the preprint server for biology
Cardiac contraction and relaxation are regulated by distinct subcellular cAMP pools.
Nature chemical biology
The organic cation Transporter 2 regulates dopamine D1 receptor signaling at the Golgi apparatus.
eLife
Emerging Role of Compartmentalized G Protein-Coupled Receptor Signaling in the Cardiovascular Field.
ACS pharmacology & translational science
Genetically Encoding Quinoline Reverses Chromophore Charge and Enables Fluorescent Protein Brightening in Acidic Vesicles.
Journal of the American Chemical Society
Functional selectivity of GPCR-directed drug action through location bias.
Nature chemical biology
Retromer Endosome Exit Domains Serve Multiple Trafficking Destinations and Regulate Local G Protein Activation by GPCRs.
Current biology : CB
The a-Arrestin ARRDC3 Regulates the Endosomal Residence Time and Intracellular Signaling of the ß2-Adrenergic Receptor.
The Journal of biological chemistry
Effects of endocytosis on receptor-mediated signaling.
Current opinion in cell biology
G protein ß? subunits regulate cardiomyocyte hypertrophy through a perinuclear Golgi phosphatidylinositol 4-phosphate hydrolysis pathway.
Molecular biology of the cell
G protein-coupled receptor (GPCR) signaling via heterotrimeric G proteins from endosomes.
The Journal of biological chemistry
Investigating signaling consequences of GPCR trafficking in the endocytic pathway.
Methods in enzymology
GPCR signaling along the endocytic pathway.
Current opinion in cell biology
Regulation of constitutive cargo transport from the trans-Golgi network to plasma membrane by Golgi-localized G protein betagamma subunits.
The Journal of biological chemistry