Tejal Desai, PhD

Professor
Bioengineering
+1 415 514-4503

Tejal Desai is the Deborah Cowan Endowed Professor, Department of Bioengineering & Therapeutic Sciences, Schools of Pharmacy and Medicine at University of California, San Francisco (UCSF); and Professor in Residence, Department of Bioengineering, UC Berkeley (UCB). She serves as director of the NIH training grant for the Joint UCSF/UCB Graduate Program in Bioengineering, and founding director of the UCSF/UCB Masters Program in Translational Medicine. She is also the Inaugural Director of the UCSF Engineering and Applied Sciences Initiative known as HIVE (Health Innovation Via Engineering).

Desai is the immediate past chair (7 years) of the Department of Bioengineering & Therapeutic Sciences.

Desai’s research spans multiple disciplines including materials engineering, cell biology, tissue engineering, and pharmacological delivery systems to develop new therapeutic interventions for disease. She seeks to design new platforms, enabled by advancements in micro and nanotechnology, to overcome existing challenges in therapeutic delivery. She has published over 250 peer-reviewed articles and patents. Her research efforts have earned recognition including Technology Review’s "Top 100 Young Innovators,” Popular Science’s Brilliant 10, and the Dawson Biotechnology Award. She is President of the American Institute for Medical and Biological Engineering and is a fellow of AIMBE, IAMBE, CRS, and BMES. In 2015, she was elected to the National Academy of Medicine and in 2019 to the National Academy of Inventors.

Desai is a vocal advocate for STEM education and outreach to women and underrepresented minority students. She serves on the university’s Differences Matter Executive Committee and her work to break down institutional barriers to equity and cultivate a climate of inclusion was recognized by the AWIS Judith Poole Award and the UCSF Chancellors Award for the Advancement of Women. As president of AIMBE, she has led advocacy efforts for increased scientific funding and addressing workforce disparities in science/engineering. To foster the next generation of scientists, she has been involved in the SF Science Education partnership and has worked with outreach organizations such as the Lawrence Hall of Science, PBS, and the UN Women’s council to develop hand-on exhibits and videos related to nanotechnology and women in engineering.

She received her B.S. from Brown University in biomedical engineering in 1994 and was awarded a Ph.D. in bioengineering jointly from UCSF and UC Berkeley in 1998.

Publications: 

Mapping hormone-regulated cell-cell interaction networks in the human breast at single-cell resolution.

Cell systems

Murrow LM, Weber RJ, Caruso JA, McGinnis CS, Phong K, Gascard P, Rabadam G, Borowsky AD, Desai TA, Thomson M, Tlsty T, Gartner ZJ

Biomaterials to enhance stem cell transplantation.

Cell stem cell

Kharbikar BN, Mohindra P, Desai TA

Synthesis and Preliminary Biological Assessment of Carborane-Loaded Theranostic Nanoparticles to Target Prostate-Specific Membrane Antigen.

ACS applied materials & interfaces

Meher N, Seo K, Wang S, Bidkar AP, Fogarty M, Dhrona S, Huang X, Tang R, Blaha C, Evans MJ, Raleigh DR, Jun YW, VanBrocklin HF, Desai TA, Wilson DM, Ozawa T, Flavell RR

Drug delivery to the anterior segment of the eye: a review of current and future treatment strategies.

International journal of pharmaceutics

Mofidfar M, Abdi B, Ahadian S, Mostafavi E, Desai TA, Abbasi F, Sun Y, Manche EE, Ta CN, Flowers CW

Theranostic biomaterials for tissue engineering.

Current opinion in biomedical engineering

Kharbikar BN, Zhong JX, Cuylear DL, Perez CA, Desai TA

Transthyretin amyloid fibrils alter primary fibroblast structure, function and inflammatory gene expression.

American journal of physiology. Heart and circulatory physiology

Dittloff KT, Iezzi A, Zhong JX, Mohindra P, Desai TA, Russell B

Bioinspired Polymeric High Aspect Ratio Particles with Asymmetric Janus Functionalities.

Advanced nanobiomed research

Finbloom JA, Cao Y, Desai TA

Micro- and nanoscale biophysical cues for cardiovascular disease therapy.

Nanomedicine : nanotechnology, biology, and medicine

Fund Black scientists.

Cell

Stevens KR, Masters KS, Imoukhuede PI, Haynes KA, Setton LA, Cosgriff-Hernandez E, Lediju Bell MA, Rangamani P, Sakiyama-Elbert SE, Finley SD, Willits RK, Koppes AN, Chesler NC, Christman KL, Allen JB, Wong JY, El-Samad H, Desai TA, Eniola-Adefeso O

Modulating the foreign body response of implants for diabetes treatment.

Advanced drug delivery reviews

Kharbikar BN, Chendke GS, Desai TA

Leadership.

Cell systems

Bowdish D, Desai TA, DePace A, Haswell ES, Baltrus D, García AJ, Deans T, Lage K, Wittkopp P

Local injections of ß-NGF accelerates endochondral fracture repair by promoting cartilage to bone conversion.

Scientific reports

Rivera KO, Russo F, Boileau RM, Tomlinson RE, Miclau T, Marcucio RS, Desai TA, Bahney CS

DNA scaffolds enable efficient and tunable functionalization of biomaterials for immune cell modulation.

Nature nanotechnology

Huang X, Williams JZ, Chang R, Li Z, Burnett CE, Hernandez-Lopez R, Setiady I, Gai E, Patterson DM, Yu W, Roybal KT, Lim WA, Desai TA

Networks of High Aspect Ratio Particles to Direct Colloidal Assembly Dynamics and Cellular Interactions.

Advanced functional materials

Finbloom JA, Demaree B, Abate AR, Desai TA

Nanotopography Enhances Dynamic Remodeling of Tight Junction Proteins through Cytosolic Liquid Complexes.

ACS nano

Huang X, Shi X, Hansen ME, Setiady I, Nemeth CL, Celli A, Huang B, Mauro T, Koval M, Desai TA

Micro and nanoscale technologies in oral drug delivery.

Advanced drug delivery reviews

Ahadian S, Finbloom JA, Mofidfar M, Diltemiz SE, Nasrollahi F, Davoodi E, Hosseini V, Mylonaki I, Sangabathuni S, Montazerian H, Fetah K, Nasiri R, Dokmeci MR, Stevens MM, Desai TA, Khademhosseini A

Engineering the drug carrier biointerface to overcome biological barriers to drug delivery.

Advanced drug delivery reviews

Finbloom JA, Sousa F, Stevens MM, Desai TA

An Injectable Cytokine Trap for Local Treatment of Autoimmune Disease.

Biomaterials

Zamecnik CR, Levy ES, Lowe MM, Zirak B, Rosenblum MD, Desai TA

Near-Infrared Optical Nanosensors for Continuous Detection of Glucose.

Journal of diabetes science and technology

Le LV, Chendke GS, Gamsey S, Wisniewski N, Desai TA

Reversible Inhibition of Efflux Transporters by Hydrogel Microdevices.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Levy ES, Samy KE, Lamson NG, Whitehead KA, Kroetz DL, Desai TA

Human intestinal spheroids cultured using Sacrificial Micromolding as a model system for studying drug transport.

Scientific reports

Samy KE, Levy ES, Phong K, Demaree B, Abate AR, Desai TA

Recent advances in intraocular sustained-release drug delivery devices.

Drug discovery today

Cao Y, Samy KE, Bernards DA, Desai TA

Bottom-Up Fabrication of Multilayer Enteric Devices for the Oral Delivery of Peptides.

Pharmaceutical research

Nemeth CL, Lykins WR, Tran H, ElSayed MEH, Desai TA

Hang on tight: reprogramming the cell with microstructural cues.

Biomedical microdevices

Le LV, Mkrtschjan MA, Russell B, Desai TA

Co-Delivery of Timolol and Brimonidine with a Polymer Thin-Film Intraocular Device.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics

Samy KE, Cao Y, Kim J, Konichi da Silva NR, Phone A, Bloomer MM, Bhisitkul RB, Desai TA

Device design methodology and formulation of a protein therapeutic for sustained release intraocular delivery.

Bioengineering & translational medicine

Schlesinger EB, Bernards DA, Chen HH, Feindt J, Cao J, Dix D, Romano C, Bhisitkul RB, Desai TA

Islet encapsulation therapy - racing towards the finish line?

Nature reviews. Endocrinology

Desai TA, Tang Q

Pro-resolving lipid mediators in vascular disease.

The Journal of clinical investigation

Conte MS, Desai TA, Wu B, Schaller M, Werlin E

Perivascular delivery of resolvin D1 inhibits neointimal hyperplasia in a rabbit vein graft model.

Journal of vascular surgery

Wu B, Werlin EC, Chen M, Mottola G, Chatterjee A, Lance KD, Bernards DA, Sansbury BE, Spite M, Desai TA, Conte MS

The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders.

Cell

Willsey AJ, Morris MT, Wang S, Willsey HR, Sun N, Teerikorpi N, Baum TB, Cagney G, Bender KJ, Desai TA, Srivastava D, Davis GW, Doudna J, Chang E, Sohal V, Lowenstein DH, Li H, Agard D, Keiser MJ, Shoichet B, von Zastrow M, Mucke L, Finkbeiner S, Gan L, Sestan N, Ward ME, Huttenhain R, Nowakowski TJ, Bellen HJ, Frank LM, Khokha MK, Lifton RP, Kampmann M, Ideker T, State MW, Krogan NJ

Stem Cell Therapies for Treating Diabetes: Progress and Remaining Challenges.

Cell stem cell

Sneddon JB, Tang Q, Stock P, Bluestone JA, Roy S, Desai T, Hebrok M

Influence of the Surfactant Structure on Photoluminescent p-Conjugated Polymer Nanoparticles: Interfacial Properties and Protein Binding.

Langmuir : the ACS journal of surfaces and colloids

Urbano L, Clifton L, Ku HK, Kendall-Troughton H, Vandera KA, Matarese BFE, Abelha T, Li P, Desai T, Dreiss CA, Barker RD, Green MA, Dailey LA, Harvey RD

Injectable hyaluronic acid based microrods provide local micromechanical and biochemical cues to attenuate cardiac fibrosis after myocardial infarction.

Biomaterials

Le LV, Mohindra P, Fang Q, Sievers RE, Mkrtschjan MA, Solis C, Safranek CW, Russell B, Lee RJ, Desai TA

Engineering a Clinically Translatable Bioartificial Pancreas to Treat Type I Diabetes.

Trends in biotechnology

Orive G, Emerich D, Khademhosseini A, Matsumoto S, Hernández RM, Pedraz JL, Desai T, Calafiore R, de Vos P

Long acting systemic HIV pre-exposure prophylaxis: an examination of the field.

Drug delivery and translational research

Lykins WR, Luecke E, Johengen D, van der Straten A, Desai TA

Lipid signaling affects primary fibroblast collective migration and anchorage in response to stiffness and microtopography.

Journal of cellular physiology

Mkrtschjan MA, Gaikwad SB, Kappenman KJ, Solís C, Dommaraju S, Le LV, Desai TA, Russell B

Injectable Polymeric Cytokine-Binding Nanowires Are Effective Tissue-Specific Immunomodulators.

ACS nano

Zamecnik CR, Lowe MM, Patterson DM, Rosenblum MD, Desai TA

Long-term intraocular pressure reduction with intracameral polycaprolactone glaucoma devices that deliver a novel anti-glaucoma agent.

Journal of controlled release : official journal of the Controlled Release Society

Kim J, Kudisch M, da Silva NRK, Asada H, Aya-Shibuya E, Bloomer MM, Mudumba S, Bhisitkul RB, Desai TA

Nanoporous Immunoprotective Device for Stem-Cell-Derived ß-Cell Replacement Therapy.

ACS nano

Chang R, Faleo G, Russ HA, Parent AV, Elledge SK, Bernards DA, Allen JL, Villanueva K, Hebrok M, Tang Q, Desai TA

Nanoengineered Stent Surface to Reduce In-Stent Restenosis in Vivo.

ACS applied materials & interfaces

Nuhn H, Blanco CE, Desai TA

Advances in islet encapsulation technologies.

Nature reviews. Drug discovery

Desai T, Shea LD

Glucose-Stimulated Insulin Response of Silicon Nanopore-Immunoprotected Islets under Convective Transport.

ACS biomaterials science & engineering

Song S, Yeung R, Park J, Posselt AM, Desai TA, Tang Q, Roy S

Calibrated flux measurements reveal a nanostructure-stimulated transcytotic pathway.

Experimental cell research

Stewart T, Koval WT, Molina SA, Bock SM, Lillard JW, Ross RF, Desai TA, Koval M

Non-autonomous cell proliferation in the mammary gland and cancer.

Current opinion in cell biology

Weber RJ, Desai TA, Gartner ZJ

Picoliter-volume inkjet printing into planar microdevice reservoirs for low-waste, high-capacity drug loading.

Bioengineering & translational medicine

Fox CB, Nemeth CL, Chevalier RW, Cantlon J, Bogdanoff DB, Hsiao JC, Desai TA

Advances in islet encapsulation technologies.

Nature reviews. Drug discovery

Desai T, Shea LD

In vivo and in vitro sustained release of ranibizumab from a nanoporous thin-film device.

Drug delivery and translational research

Lance KD, Bernards DA, Ciaccio NA, Good SD, Mendes TS, Kudisch M, Chan E, Ishikiriyama M, Bhisitkul RB, Desai TA

Rapid Organoid Reconstitution by Chemical Micromolding.

ACS biomaterials science & engineering

Weber RJ, Cerchiari AE, Delannoy LS, Garbe JC, LaBarge MA, Desai TA, Gartner ZJ

Probing the luminal microenvironment of reconstituted epithelial microtissues.

Scientific reports

Cerchiari AE, Samy KE, Todhunter ME, Schlesinger E, Henise J, Rieken C, Gartner ZJ, Desai TA

Unidirectional and sustained delivery of the proresolving lipid mediator resolvin D1 from a biodegradable thin film device.

Journal of biomedical materials research. Part A

Lance KD, Chatterjee A, Wu B, Mottola G, Nuhn H, Lee PP, Sansbury BE, Spite M, Desai TA, Conte MS

Biocompatibility and Pharmacokinetic Analysis of an Intracameral Polycaprolactone Drug Delivery Implant for Glaucoma.

Investigative ophthalmology & visual science

Kim J, Kudisch M, Mudumba S, Asada H, Aya-Shibuya E, Bhisitkul RB, Desai TA

Fabrication of Sealed Nanostraw Microdevices for Oral Drug Delivery.

ACS nano

Fox CB, Cao Y, Nemeth CL, Chirra HD, Chevalier RW, Xu AM, Melosh NA, Desai TA

Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses.

Scientific reports

Huebsch N, Loskill P, Deveshwar N, Spencer CI, Judge LM, Mandegar MA, Fox CB, Mohamed TM, Ma Z, Mathur A, Sheehan AM, Truong A, Saxton M, Yoo J, Srivastava D, Desai TA, So PL, Healy KE, Conklin BR

Perivascular delivery of resolvin D1 inhibits neointimal hyperplasia in a rat model of arterial injury.

Journal of vascular surgery

Wu B, Mottola G, Chatterjee A, Lance KD, Chen M, Siguenza IO, Desai TA, Conte MS

Silicon nanopore membrane (SNM) for islet encapsulation and immunoisolation under convective transport.

Scientific reports

Song S, Faleo G, Yeung R, Kant R, Posselt AM, Desai TA, Tang Q, Roy S

A Tunable, Biodegradable, Thin-Film Polymer Device as a Long-Acting Implant Delivering Tenofovir Alafenamide Fumarate for HIV Pre-exposure Prophylaxis.

Pharmaceutical research

Schlesinger E, Johengen D, Luecke E, Rothrock G, McGowan I, van der Straten A, Desai T

Approaching a cure for type 1 diabetes.

Nature medicine

Tang Q, Desai TA

Tunable Microfibers Suppress Fibrotic Encapsulation via Inhibition of TGFß Signaling.

Tissue engineering. Part A

Allen J, Ryu J, Maggi A, Flores B, Greer JR, Desai T

In Vitro and In Vivo Sustained Zero-Order Delivery of Rapamycin (Sirolimus) From a Biodegradable Intraocular Device.

Investigative ophthalmology & visual science

Lance KD, Good SD, Mendes TS, Ishikiriyama M, Chew P, Estes LS, Yamada K, Mudumba S, Bhisitkul RB, Desai TA

Nanotopography applications in drug delivery.

Expert opinion on drug delivery

Walsh LA, Allen JL, Desai TA

Programmed synthesis of three-dimensional tissues.

Nature methods

Todhunter ME, Jee NY, Hughes AJ, Coyle MC, Cerchiari A, Farlow J, Garbe JC, LaBarge MA, Desai TA, Gartner ZJ

Micro/nanofabricated platforms for oral drug delivery.

Journal of controlled release : official journal of the Controlled Release Society

Fox CB, Kim J, Le LV, Nemeth CL, Chirra HD, Desai TA

Polycaprolactone thin-film drug delivery systems: Empirical and predictive models for device design.

Materials science & engineering. C, Materials for biological applications

Schlesinger E, Ciaccio N, Desai TA

Polycaprolactone Thin-Film Micro- and Nanoporous Cell-Encapsulation Devices.

ACS nano

Nyitray CE, Chang R, Faleo G, Lance KD, Bernards DA, Tang Q, Desai TA

Intestinal absorption of fluorescently labeled nanoparticles.

Nanomedicine : nanotechnology, biology, and medicine

Simovic S, Song Y, Nann T, Desai TA

A strategy for tissue self-organization that is robust to cellular heterogeneity and plasticity.

Proceedings of the National Academy of Sciences of the United States of America

Cerchiari AE, Garbe JC, Jee NY, Todhunter ME, Broaders KE, Peehl DM, Desai TA, LaBarge MA, Thomson M, Gartner ZJ

Formation of spatially and geometrically controlled three-dimensional tissues in soft gels by sacrificial micromolding.

Tissue engineering. Part C, Methods

Cerchiari A, Garbe JC, Todhunter ME, Jee NY, Pinney JR, LaBarge MA, Desai TA, Gartner ZJ

Sustained delivery of MGF peptide from microrods attracts stem cells and reduces apoptosis of myocytes.

Biomedical microdevices

Doroudian G, Pinney J, Ayala P, Los T, Desai TA, Russell B

Interventional magnetic resonance imaging-guided cell transplantation into the brain with radially branched deployment.

Molecular therapy : the journal of the American Society of Gene Therapy

Silvestrini MT, Yin D, Martin AJ, Coppes VG, Mann P, Larson PS, Starr PA, Zeng X, Gupta N, Panter SS, Desai TA, Lim DA

Nanoparticulate drug delivery platforms for advancing bone infection therapies.

Expert opinion on drug delivery

Uskokovic V, Desai TA

Discrete microstructural cues for the attenuation of fibrosis following myocardial infarction.

Biomaterials

Pinney JR, Du KT, Ayala P, Fang Q, Sievers RE, Chew P, Delrosario L, Lee RJ, Desai TA

Effect of collagen nanotopography on keloid fibroblast proliferation and matrix synthesis: implications for dermal wound healing.

Tissue engineering. Part A

Muthusubramaniam L, Zaitseva T, Paukshto M, Martin G, Desai T

Planar microdevices for enhanced in vivo retention and oral bioavailability of poorly permeable drugs.

Advanced healthcare materials

Chirra HD, Shao L, Ciaccio N, Fox CB, Wade JM, Ma A, Desai TA

Mastering translational medicine: interdisciplinary education for a new generation.

Science translational medicine

Kurpinski K, Johnson T, Kumar S, Desai T, Li S

Advances in calcium phosphate coatings--anodic spark deposition: a review.

Frontiers in bioscience (Landmark edition)

Calvert KL, Desai T, Webster TJ

Membranes to achieve immunoprotection of transplanted islets.

Frontiers in bioscience (Landmark edition)

Schweicher J, Nyitray C, Desai TA

Planar bioadhesive microdevices: a new technology for oral drug delivery.

Current pharmaceutical biotechnology

Fox CB, Chirra HD, Desai TA

The effect of nanotopography on modulating protein adsorption and the fibrotic response.

Tissue engineering. Part A

Kam KR, Walsh LA, Bock SM, Ollerenshaw JD, Ross RF, Desai TA

Osteogenic and antimicrobial nanoparticulate calcium phosphate and poly-(D,L-lactide-co-glycolide) powders for the treatment of osteomyelitis.

Materials science & engineering. C, Materials for biological applications

Uskokovic V, Hoover C, Vukomanovic M, Uskokovic DP, Desai TA

NADPH oxidase inhibition prevents beta cell dysfunction induced by prolonged elevation of oleate in rodents.

Diabetologia

Koulajian K, Desai T, Liu GC, Ivovic A, Patterson JN, Tang C, El-Benna J, Joseph JW, Scholey JW, Giacca A

Ocular biocompatibility and structural integrity of micro- and nanostructured poly(caprolactone) films.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics

Bernards DA, Bhisitkul RB, Wynn P, Steedman MR, Lee OT, Wong F, Thoongsuwan S, Desai TA

Radially branched deployment for more efficient cell transplantation at the scale of the human brain.

Stereotactic and functional neurosurgery

Silvestrini MT, Yin D, Coppes VG, Mann P, Martin AJ, Larson PS, Starr PA, Gupta N, Panter SS, Desai TA, Lim DA

Nano- and microfabrication for overcoming drug delivery challenges.

Journal of materials chemistry. B

Kam KR, Desai TA

Nanostructure-mediated transport of biologics across epithelial tissue: enhancing permeability via nanotopography.

Nano letters

Kam KR, Walsh LA, Bock SM, Koval M, Fischer KE, Ross RF, Desai TA

In the spotlight: Tissue engineering.

IEEE reviews in biomedical engineering

Desai T

Nanostructured thin film polymer devices for constant-rate protein delivery.

Nano letters

Bernards DA, Lance KD, Ciaccio NA, Desai TA

Emerging microtechnologies for the development of oral drug delivery devices.

Advanced drug delivery reviews

Chirra HD, Desai TA

Characterization of dental epithelial stem cells from the mouse incisor with two-dimensional and three-dimensional platforms.

Tissue engineering. Part C, Methods

Chavez MG, Yu W, Biehs B, Harada H, Snead ML, Lee JS, Desai TA, Klein OD

Size-controlled insulin-secreting cell clusters.

Acta biomaterialia

Mendelsohn AD, Nyitray C, Sena M, Desai TA

An intact kidney slice model to investigate vasa recta properties and function in situ.

Nephron. Physiology

Crawford C, Kennedy-Lydon T, Sprott C, Desai T, Sawbridge L, Munday J, Unwin RJ, Wildman SS, Peppiatt-Wildman CM

Stem cell and biomaterials research in dental tissue engineering and regeneration.

Dental clinics of North America

Horst OV, Chavez MG, Jheon AH, Desai T, Klein OD

Single-injection HPLC method for rapid analysis of a combination drug delivery system.

AAPS PharmSciTech

Tucker RM, Parcher BW, Jones EF, Desai TA

Microdomain heterogeneity in 3D affects the mechanics of neonatal cardiac myocyte contraction.

Biomechanics and modeling in mechanobiology

Curtis MW, Budyn E, Desai TA, Samarel AM, Russell B

Glucose-induced beta cell dysfunction in vivo in rats: link between oxidative stress and endoplasmic reticulum stress.

Diabetologia

Tang C, Koulajian K, Schuiki I, Zhang L, Desai T, Ivovic A, Wang P, Robson-Doucette C, Wheeler MB, Minassian B, Volchuk A, Giacca A

Preface for the Bioinspired Assemblies and Interfaces Special Issue.

Langmuir : the ACS journal of surfaces and colloids

Armitage B, Desai T, Jiang S, Whitten D

Selective targeting of microglia by quantum dots.

Journal of neuroinflammation

Minami SS, Sun B, Popat K, Kauppinen T, Pleiss M, Zhou Y, Ward ME, Floreancig P, Mucke L, Desai T, Gan L

Collagen fibril diameter and alignment promote the quiescent keratocyte phenotype.

Journal of biomedical materials research. Part A

Muthusubramaniam L, Peng L, Zaitseva T, Paukshto M, Martin GR, Desai TA

Implanted renal replacement for end-stage renal disease.

Panminerva medica

Roy S, Goldman K, Marchant R, Zydney A, Brown D, Fleischman A, Conlisk A, Desai T, Duffy S, Humes H, Fissell W

Microtopographical assembly of cardiomyocytes.

Integrative biology : quantitative biosciences from nano to macro

Patel AA, Desai TA, Kumar S

Differentiation of human embryonic stem cells into pancreatic endoderm in patterned size-controlled clusters.

Stem cell research

Van Hoof D, Mendelsohn AD, Seerke R, Desai TA, German MS

Hierarchical nanoengineered surfaces for enhanced cytoadhesion and drug delivery.

Biomaterials

Fischer KE, Nagaraj G, Hugh Daniels R, Li E, Cowles VE, Miller JL, Bunger MD, Desai TA

Hemocompatibility of silicon-based substrates for biomedical implant applications.

Annals of biomedical engineering

Muthusubramaniam L, Lowe R, Fissell WH, Li L, Marchant RE, Desai TA, Roy S

Nanoengineered surfaces enhance drug loading and adhesion.

Nano letters

Fischer KE, Jayagopal A, Nagaraj G, Daniels RH, Li EM, Silvestrini MT, Desai TA

Patterning of mono- and multilayered pancreatic beta-cell clusters.

Langmuir : the ACS journal of surfaces and colloids

Mendelsohn AD, Bernards DA, Lowe RD, Desai TA

Nanotemplating of biodegradable polymer membranes for constant-rate drug delivery.

Advanced materials (Deerfield Beach, Fla.)

Bernards DA, Desai TA

Enhanced differentiation of retinal progenitor cells using microfabricated topographical cues.

Biomedical microdevices

Steedman MR, Tao SL, Klassen H, Desai TA

Biophysical mechanisms of single-cell interactions with microtopographical cues.

Biomedical microdevices

Patel AA, Thakar RG, Chown M, Ayala P, Desai TA, Kumar S

In the spotlight: tissue engineering.

IEEE reviews in biomedical engineering

Desai TA

Inorganic nanoporous membranes for immunoisolated cell-based drug delivery.

Advances in experimental medicine and biology

Mendelsohn A, Desai T

Whole genome expression analysis reveals differential effects of TiO2 nanotubes on vascular cells.

Nano letters

Peng L, Barczak AJ, Barbeau RA, Xiao Y, LaTempa TJ, Grimes CA, Desai TA

In vitro inflammatory response of nanostructured titania, silicon oxide, and polycaprolactone.

Journal of biomedical materials research. Part A

Ainslie KM, Tao SL, Popat KC, Daniels H, Hardev V, Grimes CA, Desai TA

Microfabricated devices for enhanced bioadhesive drug delivery: attachment to and small-molecule release through a cell monolayer under flow.

Small (Weinheim an der Bergstrasse, Germany)

Ainslie KM, Lowe RD, Beaudette TT, Petty L, Bachelder EM, Desai TA

Proliferation of mouse embryonic stem cell progeny and the spontaneous contractile activity of cardiomyocytes are affected by microtopography.

Developmental dynamics : an official publication of the American Association of Anatomists

Biehl JK, Yamanaka S, Desai TA, Boheler KR, Russell B

Long-term small molecule and protein elution from TiO2 nanotubes.

Nano letters

Peng L, Mendelsohn AD, LaTempa TJ, Yoriya S, Grimes CA, Desai TA

Biomimetic nanowire coatings for next generation adhesive drug delivery systems.

Nano letters

Fischer KE, Alemán BJ, Tao SL, Hugh Daniels R, Li EM, Bünger MD, Nagaraj G, Singh P, Zettl A, Desai TA

The effect of TiO2 nanotubes on endothelial function and smooth muscle proliferation.

Biomaterials

Peng L, Eltgroth ML, LaTempa TJ, Grimes CA, Desai TA

Contractility-dependent modulation of cell proliferation and adhesion by microscale topographical cues.

Small (Weinheim an der Bergstrasse, Germany)

Thakar RG, Chown MG, Patel A, Peng L, Kumar S, Desai TA

Retinal tissue engineering using mouse retinal progenitor cells and a novel biodegradable, thin-film poly(e-caprolactone) nanowire scaffold.

Journal of ocular biology, diseases, and informatics

Redenti S, Tao S, Yang J, Gu P, Klassen H, Saigal S, Desai T, Young MJ

Microstructures in 3D biological gels affect cell proliferation.

Tissue engineering. Part A

Norman JJ, Collins JM, Sharma S, Russell B, Desai TA

Surface modification of SU-8 for enhanced biofunctionality and nonfouling properties.

Langmuir : the ACS journal of surfaces and colloids

Tao SL, Popat KC, Norman JJ, Desai TA

Combined effects of microtopography and cyclic strain on vascular smooth muscle cell orientation.

Journal of biomechanics

Houtchens GR, Foster MD, Desai TA, Morgan EF, Wong JY

Fabrication of a layered microstructured polycaprolactone construct for 3-D tissue engineering.

Journal of biomaterials science. Polymer edition

Sarkar S, Isenberg BC, Hodis E, Leach JB, Desai TA, Wong JY

In the Spotlight: Tissue and Molecular Engineering.

IEEE reviews in biomedical engineering

Desai TA

Titania nanotubes: a novel platform for drug-eluting coatings for medical implants?

Small (Weinheim an der Bergstrasse, Germany)

Popat KC, Eltgroth M, LaTempa TJ, Grimes CA, Desai TA

A microfabricated scaffold for retinal progenitor cell grafting.

Biomaterials

Neeley WL, Redenti S, Klassen H, Tao S, Desai T, Young MJ, Langer R

Purified and surfactant-free coenzyme Q10-loaded biodegradable nanoparticles.

International journal of pharmaceutics

Nehilla BJ, Bergkvist M, Popat KC, Desai TA

Imaging cellular responses to mechanical stimuli within three-dimensional tissue constructs.

Microscopy research and technique

Tan W, Vinegoni C, Norman JJ, Desai TA, Boppart SA

Influence of engineered titania nanotubular surfaces on bone cells.

Biomaterials

Popat KC, Leoni L, Grimes CA, Desai TA

Osteogenic differentiation of marrow stromal cells cultured on nanoporous alumina surfaces.

Journal of biomedical materials research. Part A

Popat KC, Chatvanichkul KI, Barnes GL, Latempa TJ, Grimes CA, Desai TA

Biocompatibility of nanoporous alumina membranes for immunoisolation.

Biomaterials

La Flamme KE, Popat KC, Leoni L, Markiewicz E, La Tempa TJ, Roman BB, Grimes CA, Desai TA

The effects of cell density and device arrangement on the behavior of macroencapsulated beta-cells.

Cell transplantation

La Flamme KE, LaTempa TJ, Grimes CA, Desai TA

Optical coherence tomography of cell dynamics in three-dimensional tissue models.

Optics express

Tan W, Oldenburg AL, Norman JJ, Desai TA, Boppart SA

Nanostructured surfaces for bone biotemplating applications.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Popat KC, Daniels RH, Dubrow RS, Hardev V, Desai TA

Expression of superficial zone protein in mandibular condyle cartilage.

Osteoarthritis and cartilage

Ohno S, Schmid T, Tanne Y, Kamiya T, Honda K, Ohno-Nakahara M, Swentko N, Desai TA, Tanne K, Knudson CB, Knudson W

Methods for fabrication of nanoscale topography for tissue engineering scaffolds.

Annals of biomedical engineering

Norman JJ, Desai TA

Drug delivery in the BME curricula.

Annals of biomedical engineering

Saltzman M, Desai T

Expression, localization and hormonal control of angiopoietin-1 in the rhesus macaque endometrium: potential role in spiral artery growth.

Molecular human reproduction

Nayak NR, Kuo CJ, Desai TA, Wiegand SJ, Lasley BL, Giudice LC, Brenner RM

Functional MR microimaging of pancreatic beta-cell activation.

Cell transplantation

Gimi B, Leoni L, Oberholzer J, Braun M, Avila J, Wang Y, Desai T, Philipson LH, Magin RL, Roman BB

Micromachined devices: the impact of controlled geometry from cell-targeting to bioavailability.

Journal of controlled release : official journal of the Controlled Release Society

Tao SL, Desai TA

Nanoporous alumina capsules for cellular macroencapsulation: transport and biocompatibility.

Diabetes technology & therapeutics

La Flamme KE, Mor G, Gong D, La Tempa T, Fusaro VA, Grimes CA, Desai TA

Modeling of RGDC film parameters using X-ray photoelectron spectroscopy.

Langmuir : the ACS journal of surfaces and colloids

Popat KC, Leary Swan EE, Desai TA

Gastrointestinal patch systems for oral drug delivery.

Drug discovery today

Tao SL, Desai TA

Peptide-conjugated quantum dots activate neuronal receptors and initiate downstream signaling of neurite growth.

Nano letters

Vu TQ, Maddipati R, Blute TA, Nehilla BJ, Nusblat L, Desai TA

Fabrication and evaluation of nanoporous alumina membranes for osteoblast culture.

Journal of biomedical materials research. Part A

Swan EE, Popat KC, Grimes CA, Desai TA

Microscale multilayer cocultures for biomimetic blood vessels.

Journal of biomedical materials research. Part A

Tan W, Desai TA

Nanostructured antifouling poly(ethylene glycol) films for silicon-based microsystems.

Journal of nanoscience and nanotechnology

Sharma S, Desai TA

Influence of nanoporous alumina membranes on long-term osteoblast response.

Biomaterials

Popat KC, Leary Swan EE, Mukhatyar V, Chatvanichkul KI, Mor GK, Grimes CA, Desai TA

Nanoporous microsystems for islet cell replacement.

Advanced drug delivery reviews

Desai TA, West T, Cohen M, Boiarski T, Rampersaud A

XPS and AFM analysis of antifouling PEG interfaces for microfabricated silicon biosensors.

Biosensors & bioelectronics

Sharma S, Johnson RW, Desai TA

Surface modification of nanoporous alumina surfaces with poly(ethylene glycol).

Langmuir : the ACS journal of surfaces and colloids

Popat KC, Mor G, Grimes CA, Desai TA

Neurotransmitter analog tethered to a silicon platform for neuro-BioMEMS applications.

Biotechnology and bioengineering

Nehilla BJ, Popat KC, Vu TQ, Chowdhury S, Standaert RF, Pepperberg DR, Desai TA

A wireless, remote query glucose biosensor based on a pH-sensitive polymer.

Analytical chemistry

Cai Q, Zeng K, Ruan C, Desai TA, Grimes CA

Micromachined biocapsules for cell-based sensing and delivery.

Advanced drug delivery reviews

Leoni L, Desai TA

Evaluation of the stability of nonfouling ultrathin poly(ethylene glycol) films for silicon-based microdevices.

Langmuir : the ACS journal of surfaces and colloids

Sharma S, Johnson RW, Desai TA

Characterization of PC12 cell proliferation and differentiation-stimulated by ECM adhesion proteins and neurotrophic factors.

Journal of materials science. Materials in medicine

Attiah DG, Kopher RA, Desai TA

Synthesis of cytoadhesive poly(methylmethacrylate) for applications in targeted drug delivery.

Journal of biomedical materials research. Part A

Tao SL, Lubeley MW, Desai TA

Microfabricated grooves recapitulate neonatal myocyte connexin43 and N-cadherin expression and localization.

Journal of biomedical materials research. Part A

Motlagh D, Hartman TJ, Desai TA, Russell B

Assembly and characterization of biofunctional neurotransmitter-immobilized surfaces for interaction with postsynaptic membrane receptors.

Journal of biomedical materials research. Part A

Saifuddin U, Vu TQ, Rezac M, Qian H, Pepperberg DR, Desai TA

Inhibition of fibroblast proliferation in cardiac myocyte cultures by surface microtopography.

American journal of physiology. Cell physiology

Boateng SY, Hartman TJ, Ahluwalia N, Vidula H, Desai TA, Russell B

Bioadhesive poly(methyl methacrylate) microdevices for controlled drug delivery.

Journal of controlled release : official journal of the Controlled Release Society

Tao SL, Lubeley MW, Desai TA

Microfabricated drug delivery systems: from particles to pores.

Advanced drug delivery reviews

Tao SL, Desai TA

Microfabrication technology for pancreatic cell encapsulation.

Expert opinion on biological therapy

Desai TA

Bioadhesive microdevices with multiple reservoirs: a new platform for oral drug delivery.

Journal of controlled release : official journal of the Controlled Release Society

Ahmed A, Bonner C, Desai TA

Characterization of proteins and fibroblasts on thin inorganic films.

Journal of materials science. Materials in medicine

Giannoulis CS, Desai TA

Microscale three-dimensional polymeric platforms for in vitro cell culture systems.

Journal of biomaterials science. Polymer edition

Snyder JD, Desai TA

Fabrication of microtextured membranes for cardiac myocyte attachment and orientation.

Journal of biomedical materials research

Deutsch J, Motlagh D, Russell B, Desai TA

Nanoporous anti-fouling silicon membranes for biosensor applications.

Biosensors & bioelectronics

Desai TA, Hansford DJ, Leoni L, Essenpreis M, Ferrari M

Microfabricated biocapsules provide short-term immunoisolation of insulinoma xenografts.

Biomedical microdevices

Desai TA, Chu WH, Rasi G, Sinibaldi-Vallebona P, Guarino E, Ferrari M

Proteins and cells on PEG immobilized silicon surfaces.

Biomaterials

Zhang M, Desai T, Ferrari M

Microfabricated immunoisolating biocapsules.

Biotechnology and bioengineering

Desai TA, Chu WH, Tu JK, Beattie GM, Hayek A, Ferrari M

Sympathetic and baroreceptor reflex function in neurally mediated syncope evoked by tilt.

The Journal of clinical investigation

Mosqueda-Garcia R, Furlan R, Fernandez-Violante R, Desai T, Snell M, Jarai Z, Ananthram V, Robertson RM, Robertson D