Tamara Alliston, PhD

Professor
M_Ortho-Gen Ortho-Core
+1 415 502-6523

Our research focuses on the mechanobiologic pathways controlling stem cell and skeletal cell differentiation in bone and cartilage. We seek to understand how these pathways maintain the mechanical integrity of the healthy skeleton, and how this is disrupted in skeletal diseases like arthritis and osteoporosis.

In particular, we study the mechanobiology of TGFβ in the skeleton. To answer these questions we combine molecular, cellular, physiologic, bioengineering, and materials science approaches. This interdisciplinary approach will advance the development of therapies that can prevent skeletal disease and improve the speed and success of skeletal tissue regeneration.

Publications

Preclinical perspectives on disorders of the temporomandibular joint: Tracing the past, navigating the present, and shaping the future.

The journal of pain

Neubert JK, Allen K, Alliston T, Almarza AJ, Athanasiou KA, Donertas-Ayaz B, de Paula BB, Bavarian R, Bhutani N, Cairns BE, Caudle RM, Chai Y, Chen JF, Chen Y, Clark GT, Cruz-Almeida Y, DaSilva AF, Durham PL, Estela AV, Embree M, Fillingim R, Guastaldi F, Handa S, Kapila SD, Keith D, Kirkwood KL, Kramer P, Martucci KT, Murphy NP, Nackley AG, Ohrbach R, Sagl B, Smith SB, Tao F, Winkelstein B, Yao H, Young S, Gold MS

The tissue diagnostic instrument.

The Review of scientific instruments

Hansma P, Yu H, Schultz D, Rodriguez A, Yurtsev EA, Orr J, Tang S, Miller J, Wallace J, Zok F, Li C, Souza R, Proctor A, Brimer D, Nogues-Solan X, Mellbovsky L, Peña MJ, Diez-Ferrer O, Mathews P, Randall C, Kuo A, Chen C, Peters M, Kohn D, Buckley J, Li X, Pruitt L, Diez-Perez A, Alliston T, Weaver V, Lotz J