Dorit Ron, PhD

Professor In Residence
M_Neurology
[email protected]
+1 415 502-7068

Dr. Ron is a Professor in the Department of Neurology at UCSF, and is a member of the Neuroscience Graduate Program. She is also the Endowed Chair in Cell Biology of Addiction in Neurology at UCSF, the Director for a P50 NIH-NIAAA Center Grant. She is a recipient of several NIH RO1 and DOD grant awards. In 2013, Dr. Ron received and NIH MERIT. She has served as an Associate Editor for the Journal of Neuroscience and is currently a reviewing editor for Addiction Biology, the Alcohol Journal, as well as a field editor for Alcoholism: Clinical and Experimental Research. Dr. Ron’s research focuses on the molecular neurobiology of alcohol use disorders for which her laboratory uses molecular, and rodent behavior approaches. Dr. Ron’s areas of expertise are: molecular neuroscience, signal transduction, neurobiology of addiction and psychiatric disorders. Over the years the Ron lab has made numerous major contributions to the field of addiction and identified novel targets that could potentially be developed as therapeutics to treat alcohol addiction. Several of the studies resulted in UCSF press releases, which received the attention of both the scientific community and the general public.

Publications

A non-hallucinogenic psychedelic analogue with therapeutic potential.

Nature

Cameron LP, Tombari RJ, Lu J, Pell AJ, Hurley ZQ, Ehinger Y, Vargas MV, McCarroll MN, Taylor JC, Myers-Turnbull D, Liu T, Yaghoobi B, Laskowski LJ, Anderson EI, Zhang G, Viswanathan J, Brown BM, Tjia M, Dunlap LE, Rabow ZT, Fiehn O, Wulff H, McCorvy JD, Lein PJ, Kokel D, Ron D, Peters J, Zuo Y, Olson DE

Alcohol: Clin Exp Res

Recent advances in the discovery and preclinical testing of novel compounds for the prevention and/or treatment of alcohol use disorders

Davies DL, Bortolato M, Finn DA, Ramaker MJ, Barak S, Ron D, Liang J, Olsen RW

J Neurochem

Dopamine D2 receptor activation leads to an upregulation of glial cell line-derived neurotrophic factor via Gbetagamma-Erk1/2-dependent induction of Zif268

Ahmadiantehrani S and Ron D

Transl Psychiatry

Chromatin remodeling - A novel strategy to control excessive alcohol drinking.

Warnault V, Darcq E, Levine A, Barak S, Ron D.

Addic Biol

Alpha4 subunit-containing GABA(A) receptors in the accumbens shell contribute to the reinforcing effects of alcohol.

Rewal M, Donahue R, Gill TM, Nie H, Ron D, Janak PH.

J Biol Chem

Direct interaction between scaffolding proteins RACK1 and 14-3-3zeta regulates brain-derived neurotrophic factor (BDNF) transcription.

Neasta J, Kiely PA, He DY, Adams DR, O'Connor R, Ron D.

J Neurosci

The small G protein H-Ras in the mesolimbic system is a molecular gateway to alcohol-seeking and excessive drinking behaviors

Ben Hamida S, Neasta J, Lasek AW, Kharazia V, Zou M, Carnicella S, Janak PH, Ron D.

J Neurosci

Ethanol-mediated facilitation of AMPA receptor function in the dorsomedial striatum: Implications for alcohol drinking behavior

Wang J, Ben Hamida S, Darcq E, Zhu W, Gibb SL, Lanfranco MF, Carnicella S and Ron D.

J Neurochem

Ethanol-induced increase in Fyn kinase activity in the dorsomedial striatum is associated with subcellular redistribution of protein tyrosine phosphatase alpha

Gibb SL, Ben Hamida S, Lanfranco MF, Ron D

J Neurochem

Ethanol-induced increase in Fyn kinase activity in the dorsomedial striatum is associated with subcellular redistribution of protein tyrosine phosphatase alpha.

Gibb SL, Hamida SB, Lanfranco MF, Ron D.