PNAS nexus

Neuroinflammation generated by HIV-infected microglia promotes dysfunction and death of neurons in human brain organoids.

PNAS nexus

Kong W, Frouard J, Xie G, Corley MJ, Helmy E, Zhang G, Schwarzer R, Montano M, Sohn P, Roan NR, Ndhlovu LC, Gan L, Greene WC

Neuroinflammation generated by HIV-infected microglia promotes dysfunction and death of neurons in human brain organoids.

PNAS nexus

Weili Kong, Julie Frouard, Guorui Xie, Michael J Corley, Ekram Helmy, Gang Zhang, Roland Schwarzer, Mauricio Montano, Peter Sohn, Nadia R Roan, Lishomwa C Ndhlovu, Li Gan, Warner C Greene

Type 2 diabetes impairs annulus fibrosus fiber deformation and rotation under disc compression in the University of California Davis type 2 diabetes mellitus (UCD-T2DM) rat model.

PNAS nexus

Rosenberg JL, Schaible E, Bostrom A, Lazar AA, Graham JL, Stanhope KL, Ritchie RO, Alliston TN, Lotz JC, Havel PJ, Acevedo C, Fields AJ

Type 2 diabetes impairs annulus fibrosus fiber deformation and rotation under disc compression in the UCD-T2DM rat model.

PNAS nexus

James L Rosenberg, Eric Schaible, Alan Bostrom, Ann A Lazar, James L Graham, Kimber L Stanhope, Robert O Ritchie, Tamara N Alliston, Jeffrey C Lotz, Peter J Havel, Claire Acevedo, Aaron J Fields

Aldehyde dehydrogenase 3A1 deficiency leads to mitochondrial dysfunction and impacts salivary gland stem cell phenotype.

PNAS nexus

Viswanathan V, Cao H, Saiki J, Jiang D, Mattingly A, Nambiar D, Bloomstein J, Li Y, Jiang S, Chamoli M, Sirjani D, Kaplan M, Holsinger FC, Liang R, Von Eyben R, Jiang H, Guan L, Lagory E, Feng Z, Nolan G, Ye J, Denko N, Knox S, Rosen DM, Le QT