eLife

Antibacterial potency of type VI amidase effector toxins is dependent on substrate topology and cellular context.

eLife

Radkov A, Sapiro AL, Flores S, Henderson C, Saunders H, Kim R, Massa S, Thompson S, Mateusiak C, Biboy J, Zhao Z, Starita LM, Hatleberg WL, Vollmer W, Russell AB, Simorre JP, Anthony-Cahill S, Brzovic P, Hayes B, Chou S

Correction: mTORC1 in the orbitofrontal cortex promotes habitual alcohol seeking.

eLife

Morisot N, Phamluong K, Ehinger Y, Berger AL, Moffat JJ, Ron D

Directed evolution of the rRNA methylating enzyme Cfr reveals molecular basis of antibiotic resistance.

eLife

Tsai K, Stojkovic V, Noda-Garcia L, Young ID, Myasnikov AG, Kleinman J, Palla A, Floor SN, Frost A, Fraser JS, Tawfik DS, Fujimori DG

Regulatory T-cells inhibit microglia-induced pain hypersensitivity in female mice.

eLife

Kuhn J, Vainchtein ID, Braz JM, Hamel K, Bernstein M, Craik V, Dahlgren MW, Ortiz-Carpena J, Molofsky A, Molofsky A, Basbaum A

A zebrafish screen reveals Renin-angiotensin system inhibitors as neuroprotective via mitochondrial restoration in dopamine neurons.

eLife

Kim GJ, Mo H, Liu H, Wu Z, Chen S, Zheng J, Zhao X, Nucum D, Shortland J, Peng L, Elepano M, Tang B, Olson S, Paras N, Li H, Renslo AR, Arkin MR, Huang B, Lu B, Sirota M, Guo S

Cortical astrocytes independently regulate sleep depth and duration via separate GPCR pathways.

eLife

Vaidyanathan TV, Collard M, Yokoyama S, Reitman ME, Poskanzer KE

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