Rosemary Akhurst, PhD

Professor In Residence
M_HDF Comprehensive Cancer Ctr

TGFβ signaling is important in cancer, vascular, and stem cell biology, as well as tumor drug-resistance and immunotherapy. We study how TGFβ regulates these processes in vivo, and how genetic variation affects TGFβ related diseases and drug outcomes.

Akhurst Lab

Publications

Cross-Species and Tissue-Agnostic Prediction of Human Cancer Treatment Response using AI-Powered Cellular Morphometric Biomarkers from a Genetically Diverse Erbb2 Mouse Model.

medRxiv : the preprint server for health sciences

Perez-Baena MJ, Blanco-Gomez A, Jimenez-Navas A, Rodriguez-Gonzalez M, Abad-Hernandez MDM, Taylor MA, Mendiburu-Elicabe M, Garcia-Sancha N, Corchado-Cobos R, Rodriguez-Sanchez CA, Cruz-Hernandez JJ, Fonseca E, Jen KY, Holgado-Madruga M, Akhurst RJ, Balmain A, Mao JH, Perez-Losada J, Chang H

Erratum: Mouse and human strategies identify PTPN14 as a modifier of angiogenesis and hereditary haemorrhagic telangiectasia.

Nature communications

Michael Benzinou, Frederic F. Clermont, Tom G W. Letteboer, Jai-hyun Kim, Silvia Espejel, Kelly A. Harradine, Juan Arbelaez, Minh Thu Luu, Ritu Roy, David Quigley, Mamie Nakayama Higgins, Musa Zaid, Bradley E. Aouizerat, Johannes Kristian Ploos van Amstel, Sophie Giraud, Sophie Dupuis-Girod, Gaetan Lesca, Henri Plauchu, Christopher C W. Hughes, Cornelius J.J. Westermann, Rosemary J. Akhurst

Dev. Biol

Differential expression of the actin gene family of Strongylocentrotus purpuratus

Akhurst RJ (Shott RJ) Lee JJ, Britten RJ, Davidson EH